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Acute lymphocytic leukemia

[ACUTE MONOCYTIC LEUKEMIA (AML-M5b)]. Another case showing promonocytes with nuclear folds and creases. Nuclear folds and indentations may also be seen in cases of microgranular acute promyelocytic leukemia (APL-M3v) but Auer rods can easily be identified in most cases of APL-M3v. Flow cytometric analysis of acute monocytic leukemia shows almost consistent expression of HLA-DR and CD33 and often that of CD117 and CD13. However, CD34 is generally negative M5b and more often positive in M5a…


Shark skin under electron microscope

Leukemia cells

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Chronic lymphocytic leukemia. The peripheral blood smear shows an absolute lymphocytosis of small “mature” lymphocytes with clumped, smudgy chromatin and scant cytoplasm. Smudge cells

Leukemias & Lymphomas you must know

[ACUTE MONOCYTIC LEUKEMIA (AML-M5b)]. This leukemia is predominantly composed of promonocytes that show moderate amounts of cytoplasm and large nuclei with fine chromatin but without prominent nucleoli. Note presence of nuclear folds and creases, which are a characteristic feature of promonocytes.

Promyelocyte with Auer rods. If in blood or in bone marrow: Acute Promyelocytic Leukemia (APL)