lucrezia borgia illegitimate daughter of Pope Alexander VI (Rodrigo Borgia) by one of his mistresses, Lucrezia Borgia gained a reputation as a poisoner and plotter. She was more likely a victim of malicious gossip that exaggerated her actual misdoings, and likely was not an active participant in her father's and brother's infamous plots.
Leonardo da Vinci, Cesare Borgia, Michelangelo Buonarrotti by Fuyumi Soryo.
Giovio, Paolo, 1483-1552 Portrait of Cesare Borgia, son of Pope Alexander VI and Duke of Valentinois, Italian condottiero. Courtesy of the Digital Image Archive, Pitts Theology Library, Candler School of Theology, Emory University.